Ignition timing and Boost

I have a twin turbo hemi with fuel heads. Can't seem to find lots out there about turbo stuff.
We are very conservative on igntion timing, this engine with a blower ran 28 degrees at 45lbs. The only thing different is it now has efi, turbos and coil on plug.
So my question, have any of you guys swapped to a different power adder and does it effect timing. If you changed nothing on the engine and went to a procharger or turbos. Would timing change?

 

You say you changed Ignition. If your new ignition has increased your Millijouels more than likely it will require less timing also. So watch that in your tune up.